Author/Authors :
Quevedo، نويسنده , , Rodolfo and Baquero، نويسنده , , Edwin and Rodriguez، نويسنده , , Mario، نويسنده ,
Abstract :
Regioselectivity in isoquinoline alkaloid synthesis is analyzed here. Our experiments have shown that substituents on the aromatic ring of the starting amine are determinant in isoquinoline synthesis. The use of dicyclohexylcarbodiimide in activating carboxylic acids for electrophilic aromatic substitution reactions is presented for the first time.
