Title of article
Diselenophosphinates of lupinine or anabasine via a new three-component reaction of secondary phosphines, elemental selenium, and amines
Author/Authors
Gusarova، نويسنده , , Nina K. and Artemʹev، نويسنده , , Alexander V. and Malysheva، نويسنده , , Svetlana F. and Fedorov، نويسنده , , Sergei V. and Kazheva، نويسنده , , Olga N. and Alexandrov، نويسنده , , Grigorii G. and Dyachenko، نويسنده , , Oleg A. and Trofimov، نويسنده , , Boris A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
1840
To page
1843
Abstract
Secondary phosphines, elemental selenium, and the natural alkaloids, lupinine and anabasine, interact in a three-component-type reaction under mild conditions (70 °C, 1–1.5 h, EtOH) without the formation of any by-products to give diselenophosphinates of the above-mentioned alkaloids (in almost quantitative yields) with the retention of their intrinsic optical activity. Thus, the developed synthesis represents an atom-economic route to new selenophosphorus derivatives of alkaloids.
Keywords
secondary phosphines , elemental selenium , Anabasine , Lupinine , Diselenophosphinates
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871652
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