Title of article :
Synthetic studies toward the development of novel minoxidil analogs and conjugates with polyamines
Author/Authors :
Magoulas، نويسنده , , George E. and Bariamis، نويسنده , , Stavros E. and Athanassopoulos، نويسنده , , Constantinos M. and Papaioannou، نويسنده , , Dionissios، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
Syntheses of novel polyamine-modified minoxidil analogs (PMMs) and minoxidil–polyamine conjugates (MPCs) are described in an effort to improve the biological activity and selectivity of minoxidil and its poor solubility in water.
Keywords :
nucleophilic aromatic substitution , pyrimidines , N?-Carbonyldiimidazole , N , Minoxidil , polyamine conjugates , N-oxides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
