Title of article
Fe(II)-catalyzed N-alkylation of sulfonamides with benzylic alcohols
Author/Authors
Cui، نويسنده , , Xinjiang and Shi، نويسنده , , Feng and Zhang، نويسنده , , Yan and Deng، نويسنده , , Youquan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
2048
To page
2051
Abstract
The FeCl2/K2CO3 catalyst system was developed successfully for the N-alkylation of sulfonamides with benzylic alcohols via borrowing hydrogen method. XPS analysis suggested a possible catalyst cycle between Fe(II) and Fe(0). Under the optimized condition, the scope of the protocol was demonstrated in 21 different alkylation reactions. High yields, in general >90%, are achieved in most cases.
Keywords
Sulfonamide , alcohol , Iron , Alkylation
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871926
Link To Document