Title of article :
Carbon tether rigidity as a stereochemical tool directing intramolecular radical cyclizations
Author/Authors :
Melikyan، نويسنده , , Gagik G. and Voorhees، نويسنده , , Erin and Wild، نويسنده , , Christopher and Spencer، نويسنده , , Ryan and Molnar، نويسنده , , Justin، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
The phenyl group incorporated into a carbon tether provides for the synthesis of 1,5-cyclodecadiynes with 95–100% d,l-diastereoselectivity due to intrinsic conformational constraints and preorganization of the Co2(CO)6-complexed propargyl intermediates.
Keywords :
Chemoselectivity , diastereoselectivity , Cobalt , Intramolecular cyclization , Propargyl radical
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
