Title of article
Carbon tether rigidity as a stereochemical tool directing intramolecular radical cyclizations
Author/Authors
Melikyan، نويسنده , , Gagik G. and Voorhees، نويسنده , , Erin and Wild، نويسنده , , Christopher and Spencer، نويسنده , , Ryan and Molnar، نويسنده , , Justin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
2287
To page
2290
Abstract
The phenyl group incorporated into a carbon tether provides for the synthesis of 1,5-cyclodecadiynes with 95–100% d,l-diastereoselectivity due to intrinsic conformational constraints and preorganization of the Co2(CO)6-complexed propargyl intermediates.
Keywords
Chemoselectivity , diastereoselectivity , Cobalt , Intramolecular cyclization , Propargyl radical
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1872047
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