Title of article
Development of thiol-responsive amide bond cleavage device and its application for peptide nucleic acid-based DNA releasing system
Author/Authors
Shigenaga، نويسنده , , Akira and Yamamoto، نويسنده , , Jun and Hirakawa، نويسنده , , Hiroko and Ogura، نويسنده , , Keiji and Maeda، نويسنده , , Nami and Morishita، نويسنده , , Ko and Otaka، نويسنده , , Akira، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
2525
To page
2528
Abstract
To develop a thiol-responsive DNA-releasing system, a thiol-responsive amino acid capable of inducing an amide bond cleavage in the presence of a thiol was developed. It was successfully combined with peptide nucleic acid (PNA), and thiol-induced release of DNA from the thiol-responsive PNA/DNA complex was observed.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1872126
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