Title of article
Second-generation synthesis of endogenous sperm-activating and attracting factor (SAAF) isolated from the ascidian Ciona intestinalis
Author/Authors
Oishi، نويسنده , , Tohru and Ootou، نويسنده , , Kouichiro and Shibata، نويسنده , , Hajime and Murata، نويسنده , , Michio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
2600
To page
2602
Abstract
Stereoselective synthesis of the chemoattractant sperm-activating and attracting factor (SAAF), isolated from the eggs of the ascidian Ciona intestinalis, was achieved via reductive 1,3-transposition of an allylic alcohol and the axial opening of an epoxide as key steps. This second-generation synthesis improved the total yield of SAAF over that of the first-generation synthesis and provided a key intermediate for synthesizing molecular probes of SAAF.
Keywords
Chemoattractant , sperm-activating and attracting factor , Sterol sulfate , stereoselective synthesis
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1872145
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