The first total synthesis of potent human chymase inhibitor SPF32629B via regioselective bromination and O-acylation strategy
Author/Authors :
Vegi Maheswara Rao، نويسنده , , Srinivasa Rao and Boovanahalli، نويسنده , , Shanthaveerappa K. and Patro، نويسنده , , Balaram and Mukkanti، نويسنده , , K.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Pages :
3
From page :
2768
To page :
2770
Abstract :
An efficient total synthesis of (±)-SPF32629B is described. The key features of the synthesis include regioselective bromination followed by carboxylation at C-3 and protecting-group-free regioselective acylation of hydroxyl group present at C7. Structure was determined by X-ray analysis.
