Author/Authors :
Guo، نويسنده , , Chuangxing and Dong، نويسنده , , Liming and Kephart، نويسنده , , Susan and Hou، نويسنده , , Xinjun، نويسنده ,
Abstract :
Here we report an efficient synthesis of sulfamides. 3,5-Lutidine was found to be an optimal solvent and catalyst for the reaction. The method was developed during our efforts to synthesize a series of novel FKBP-12 inhibitors in which the known ketoamide linker was replaced with sulfamide.
