Author/Authors :
Neuenfeldt، نويسنده , , Patrيcia D. and Drawanz، نويسنده , , Bruna B. and Siqueira، نويسنده , , Geonir M. and Gomes، نويسنده , , Claudia R.B. and Wardell، نويسنده , , Solange M.S.V. and Flores، نويسنده , , Alex F.C. and Cunico، نويسنده , , Wilson، نويسنده ,
Abstract :
An efficient solvent-free synthesis of thiazolidinones from reaction of mercaptoacetic acid, aldehydes (benzaldehyde and valeraldehyde) or ketones (cyclopentanone and cyclohexanone), and hydrazines (phenylhydrazine and 2,4-dinitrophenylhydrazine) is reported. The compounds were generally characterized by spectroscopic techniques and specifically for 2-cyclohexanyl-3-(N-phenyl)-1,3-thiazolidin-4-one by X-ray crystallography.
Keywords :
Thiazolidinones , Hydrazones , Heterocycles , Solvent free
