Author/Authors :
Venkata Prasad، نويسنده , , J. and Prabhakar، نويسنده , , Maddela and Manjulatha، نويسنده , , K. and Rambabu، نويسنده , , D. and Anand Solomon، نويسنده , , K. and Gopi Krishna، نويسنده , , G. Sudha Anil Kumar، نويسنده , , K.، نويسنده ,
Abstract :
A novel one-pot eco-friendly protocol for the synthesis of 2-benzazepine derivatives in water has been developed. 4-Chloro-3-formyl coumarin reacts with benzyl amines under catalyst-free conditions in aqueous medium to afford substituted 5-(2′-hydroxyaryl)-4-amido-2-benzazepines in excellent yields.
Keywords :
green chemistry , Benzyl amines , Coumarin , benzazepines , catalyst-free , one-pot synthesis , Scaffold hopping
