Author/Authors :
Stabile، نويسنده , , Paolo and Lamonica، نويسنده , , Alessandro and Ribecai، نويسنده , , Arianna and Castoldi، نويسنده , , Damiano and Guercio، نويسنده , , Giuseppe and Curcuruto، نويسنده , , Ornella، نويسنده ,
Abstract :
A mild, general, convenient and practical methodology for the selective copper-mediated mono N-arylation of unprotected 2-imidazolidinone was developed. Strong electron-donating groups and free hydroxy and amino groups on the aryl iodide substrates were well tolerated. The use of n-butanol as the solvent for the copper-catalysed mono-arylation of 2-imidazolidinone is unprecedented.
Keywords :
Goldberg reaction , Copper catalysis , n-Butanol , N-aryl-2-imidazolidinones
