Author/Authors :
Popsavin، نويسنده , , Velimir and Benedekovi?، نويسنده , , Goran and Popsavin، نويسنده , , Mirjana and Koji?، نويسنده , , Vesna and Bogdanovi?، نويسنده , , Gordana، نويسنده ,
Abstract :
The first total synthesis of (+)-crassalactone B (2) and a new syntheses of (+)-crassalactone C (3) has been achieved starting from d-glucose. The natural products 2 and 3 can be selectively accessed by changing the conditions for TBDPS cleavage in the final intermediate 16. The synthesized natural products were evaluated for their cytotoxic activity against a panel of human tumour cell lines.
