Title of article
A convenient and efficient synthesis of C-carbamoyl-1,2,3-triazoles from alkyl bromide by a one-pot sequential addition: conversion of ester to amide using Zr(Ot-Bu)4
Author/Authors
Yang، نويسنده , , Dongsik and Kwon، نويسنده , , Mihyun and Jang، نويسنده , , Yujin and Jeon، نويسنده , , Heung Bae، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
5
From page
3691
To page
3695
Abstract
A convenient and efficient one-pot sequence has been developed for the synthesis of C-carbamoyl-1,2,3-triazoles from alkyl bromide using (i) sodium azide, (ii) methyl propiolate and copper iodide, and (iii) amines, zirconium tert-butoxide, and 1-hydroxybenzotriazole, under microwave irradiation. The sequential reactions in one-pot provided the desired C-carbamoyl-1,2,3-triazoles in excellent yields.
Keywords
One-pot sequence , 2 , C-Carbamoyl-1 , 3-Triazole , Zirconium tert-butoxide , microwave irradiation
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1873459
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