Author/Authors :
Hennings، نويسنده , , D.David and Watson، نويسنده , , Daniel J. and Lyssikatos، نويسنده , , Joe P. and Allen، نويسنده , , Andrew، نويسنده ,
Abstract :
A practical method for the preparation of single component biaryl-urea analogs of capreomycin is described. The protocol involves derivatization of capreomycin followed by global protection of the capreomycin analog mixture. The individual components were separated using simple flash column chromatography followed by deprotection to give the desired analogs with high purity.
