Palladium(0) nanoparticle-catalyzed sp2 C–H activation: a convenient route to alkyl–aryl ketones by direct acylation of aryl bromides and iodides with aldehydes

Palladium(0) nanoparticles efficiently catalyze aliphatic aldehyde C–H functionalization by aryl halides to produce alkyl–aryl ketones in good yields. A wide range of substituted aryl and hetero-aryl bromides/iodides and open-chain aldehydes of varied chain length participated in this reaction.