Title of article :
Pd-catalyzed one-pot chemoselective hydrogenation protocol for the preparation of carboxamides directly from azides
Author/Authors :
Sudhir N. Bavikar، نويسنده , , Sudhir N. and Salunke، نويسنده , , Deepak B. and Hazra، نويسنده , , Braja G. and Pore، نويسنده , , Vandana S. and Thierry، نويسنده , , Josiane and Dodd، نويسنده , , Robert H.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
Carboxamides were obtained efficiently in high yields from azides on reaction with the corresponding pre-formed activated carboxylic acids in a single-step reductive transformation using hydrogen atmosphere (balloon) under Pd/BaSO4 or Pd/CaCO3 catalysis. The method is highly chemoselective and compatible with extremely labile functional groups such as benzyl carbamates, benzyl ethers, benzyl esters, and olefins.
Keywords :
Azide , Carboxamide , PALLADIUM , Catalytic hydrogenation , Succinimide ester , Chemoselective
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
