Title of article
Organocatalytic approach to 3,5,6-trisubstituted and 4,6-disubstituted tetrahydropyran-2-ones
Author/Authors
Xu، نويسنده , , Danhua and Zhang، نويسنده , , Yihua and Ma، نويسنده , , Dawei، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
3827
To page
3829
Abstract
The diarylprolinol ether-catalyzed Michael addition and subsequent cyclization of ethyl 3-methyl-2-oxobut-3-enoate with aldehydes, and γ-substituted β,γ-unsaturated-α-ketoesters with acetaldehyde, afforded the corresponding lactals, which were subjected to oxidation and stereocontrolled hydrogenation to provide 3,5,6-trisubstituted and 4,6-disubstituted tetrahydropyran-2-ones with excellent enantioselectivities.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1873590
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