Author/Authors :
Kim، نويسنده , , Jeong Geun and Yang، نويسنده , , Eun Hae and Youn، نويسنده , , Woo-Sup and Choi، نويسنده , , Ji-Won and Ha، نويسنده , , Deok-Chan and Ha، نويسنده , , Jae Du، نويسنده ,
Abstract :
A simple method for microwave-assisted amination of 3-bromo-2-chloropyridine with various substituted aminoethanols is described. The reaction was carried out under microwave irradiation conditions (at 180 °C for 1–2 h) and the result was superior in terms of conversion and yield when compared to that of the corresponding conventional heating conditions.
Keywords :
Aminoethanol , 4]oxazine , 3-Bromo-2-chloropyridine , Microwave-assisted amination