Title of article :
A new method for the stereoselective construction of angular methyl group of fuzed cyclic ethers
Author/Authors :
Kadota، نويسنده , , Isao and Kishi، نويسنده , , Takayuki and Fujisawa، نويسنده , , Yuka and Yamagami، نويسنده , , Yuji and Takamura، نويسنده , , Hiroyoshi، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
A convenient method for the stereoselective construction of angular methyl group of fuzed cyclic ethers is described. Reactions of mixed thioacetals with Me2Zn/Zn(OTf)2 afforded the corresponding methylated products in good yields. Various protective groups such as MOM ether, benzylidene acetal, TBS ether, and pivaloyl group were stable under the reaction conditions.
Keywords :
Marine polycyclic ethers , Fuzed cyclic ethers , Angular methyl group , Mixed thioacetals
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
