Author/Authors :
Yadav، نويسنده , , J.S. and Das، نويسنده , , Saibal and Satyanarayana Reddy، نويسنده , , J. and Thrimurtulu، نويسنده , , N. and Prasad، نويسنده , , A.R.، نويسنده ,
Abstract :
The first total synthesis of (3R),(5R)-5-hydroxy-de-O-methyllasiodiplodin and its epimer is reported from malic acid. The adopted approach is highly convergent and stereoselective. The strategy utilizes syn selective reduction and ring-closing metathesis as key steps.