Title of article
Direct asymmetric α-hydroxymethylation of ketones in homogeneous aqueous solvents
Author/Authors
Pasternak، نويسنده , , Monika and Paradowska، نويسنده , , Joanna and Rogozi?ska، نويسنده , , Maria and Mlynarski، نويسنده , , Jacek، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
4088
To page
4090
Abstract
A chiral prolinamide-based zinc complex promotes the aldol reaction of ketones with aqueous formaldehyde, giving the corresponding adducts in good yields and high ees. The efficient direct aldol reaction of formaldehyde with ketones in homogeneous aqueous solution is presented for the first time.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1873845
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