Title of article :
A novel synthesis of 1,5-disubstituted fluorinated tetrazoles from 1,1-difluoroazides
Author/Authors :
Polivanova، نويسنده , , Anna G. and Shkavrov، نويسنده , , Sergey V. and Churakov، نويسنده , , Andrei V. and Lermontov، نويسنده , , Anatoly S. and Lermontov، نويسنده , , Sergey A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
A new one-step reaction between 1,1-difluoroazides and primary amines is reported as an efficient synthetic approach for tetrazole formation. Examples include the syntheses of fluorine-containing 1,5-substituted tetrazoles from three fluorinated azide precursors and various amines. Greater substituent diversity in comparison with conventional methods is achieved.
Keywords :
Difluoroazides , 1 , 5-Substituted fluorinated tetrazoles , Fluorine nucleophilic substitution
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
