Title of article
Salviatalin A and salvitrijudin A, two diterpenes with novel skeletons from roots of Salvia digitaloides and anti-inflammatory evaluation
Author/Authors
Wu، نويسنده , , Shwu-Jen and Chan، نويسنده , , Hsiu-Hui and Hwang، نويسنده , , Tsong-Long and Qian، نويسنده , , Keduo and Morris-Natschke، نويسنده , , Susan and Lee، نويسنده , , Kuo-Hsiung and Wu، نويسنده , , Tian-Shung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
4287
To page
4290
Abstract
Salviatalin A (1) and salvitrijudin A (2), two diterpenes with novel skeletons, were isolated from the roots of Salvia digitaloides. Their structures were determined using 1D, 2D NMR, and HRESI-MS spectroscopic analyses. Salviatalin A (1) from bioassay-guided fractionation showed a potent inhibitory effect on superoxide anion production in GMLP/CB-activated human neutrophils as well as other anti-inflammatory effects. A plausible biosynthetic pathway is also discussed.
Keywords
Salvia digitaloides , Anti-inflammatory effects , Salvitrijudin A , Salviatalin A
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1874010
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