Title of article
A novel pseudo-seven-component diastereoselective synthesis of λ5-phosphanylidene bis(2,5-dioxotetrahydro-1H-pyrrole-3-carboxylates) via binucleophilic systems
Author/Authors
Alizadeh، نويسنده , , Abdolali and Rostamnia، نويسنده , , Sadegh and Zhu، نويسنده , , Long-Guan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
5
From page
4750
To page
4754
Abstract
The unusual 1:2 intermediate, generated by the addition of triphenylphosphine (TPP) to dialkyl acetylenedicarboxylates (DAAD) was trapped during the reaction of a Ph3P/RN = C/DMAD binucleophilic system with TFA as an initial proton source in a pseudo-seven-component (7-CR) diastereoselective reaction to give λ5-phosphanylidene bis(2,5-dioxotetrahydro-1H-pyrrole-3-carboxylates) with three stereogenic centers and a phosphorane group in good yields.
Keywords
Triphenylphosphine , isocyanide , Dialkyl acetylenedicarboxylate , TFA , Phosphanylidene , Pseudo-seven-component (7-CR) reaction
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1874406
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