Title of article
Photochromic nucleic base units suitable for nucleic acid labelling
Author/Authors
Nino and Gogritchiani، نويسنده , , Eliso and Hartmann، نويسنده , , Thomas and Palm، نويسنده , , Barbara Susanne and Samsoniya، نويسنده , , Shota and Dürr، نويسنده , , Heinz، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
5
From page
18
To page
22
Abstract
New molecules incorporating a uracil nucleic base and a dihydroindolizine (DHI) unit linked via spacer arms, i.e., uracil-spyrodihydroindolizine (4), were synthesised as models for light sensitive systems for nucleic acid labelling. The uracil-DHI (4) undergoes easy photocoloration to the uracil-betaine (5) generating the UV-detectable species. Preliminary results show rather weak binding of uracil-DHI (4) to calf thymus-DNA.
Keywords
Photochromism , Dihydroindolizine , Nucleic acid labels
Journal title
Journal of Photochemistry and Photobiology B:Biology
Serial Year
2002
Journal title
Journal of Photochemistry and Photobiology B:Biology
Record number
1874445
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