Author/Authors :
Feng، نويسنده , , Yunjiang and Davis، نويسنده , , Rohan A. and Sykes، نويسنده , , Melissa L. and Avery، نويسنده , , Vicky M. and Camp، نويسنده , , David and Quinn، نويسنده , , Ronald J.، نويسنده ,
Abstract :
Mass-directed fractionation based on a Trypanosoma brucei brucei active fraction from the Australian sponge Pseudoceratina sp. led to the isolation of a novel bromotyrosine alkaloid, pseudoceratinazole A (1). Compound 1 is the first dimeric bromotyrosine alkaloid containing an imidazole-bridging moiety.
