Author/Authors :
Shen، نويسنده , , Li and Cao، نويسنده , , Song and Wu، نويسنده , , Jingjing and Li، نويسنده , , Hui and Zhang، نويسنده , , Jian and Wu، نويسنده , , Mingxi and Qian، نويسنده , , Xuhong، نويسنده ,
Abstract :
A novel synthesis of 2-trifluoromethyl-6-difluoromethylpyridine-3,5-dicarboxylates by three-component reaction of ethyl trifluoroacetoacetate, aldehydes, and ammonium acetate in the presence of K2CO3 under solvent-free conditions via sequential Hantzsch reaction/dehydration/dehydrofluorination in a one-pot process was described.
