Title of article
Highly effective and enantioselective α-amination of aldehydes promoted by chiral proline amide–thiourea bifunctional catalysts
Author/Authors
Fu، نويسنده , , Ji-Ya and Huang، نويسنده , , Qing-chun and Wang، نويسنده , , Qiao-Wei and Wang، نويسنده , , Li-Xin and Xu، نويسنده , , Xiao-Ying، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
4870
To page
4873
Abstract
A series of secondary amine–thiourea catalysts derived from l-proline and chiral diamine were prepared and successfully applied to the highly effective and enantioselective α-amination of unmodified aldehydes with various azodicarboxylates in excellent yields (up to 99%) and enantioselectivities (up to 99% ee) within a few minutes.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1874515
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