Title of article
An expedient synthesis of indolo[1,2-a]quinolines via Mn(OAc)3-mediated oxidative free radical cyclization and NaI/O2-assisted dealkoxycarbonylation/aerobic oxidation cascade
Author/Authors
Lee، نويسنده , , Hyun Seung and Kim، نويسنده , , Se-Hee and Kim، نويسنده , , Yu Mi and Kim، نويسنده , , Jae Nyoung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
5
From page
5071
To page
5075
Abstract
An expedient synthetic procedure of indolo[1,2-a]quinolines was developed using a sequential Cu-mediated N-arylation of indole, Mn(OAc)3-mediated oxidative free radical cyclization, and NaI/O2-assisted concomitant dealkoxycarbonylation/aerobic oxidation. The last step was replaced by a palladium-catalyzed decarboxylation/elimination protocol for the allyl ester derivatives.
Keywords
2-a]quinolines , Mn(OAc)3 , Dealkoxycarbonylation , Aerobic oxidation
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1874702
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