Title of article
Synthesis of condensed heterocycles via cyclopropylimine rearrangement of cyclopropylazoles
Author/Authors
Tomilov، نويسنده , , Yury V. and Platonov، نويسنده , , Dmitry N. and Frumkin، نويسنده , , Aleksandr E. and Lipilin، نويسنده , , Dmitry L. and Salikov، نويسنده , , Rinat F. Salikov، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
5120
To page
5123
Abstract
Thermal cyclopropylimine rearrangement of cyclopropylazoles into condensed heterocycles and factors affecting the regioselectivity and conversion are reported. A method of conducting the reaction in the absence of solvents is developed. A series of 2-cyclopropylazoles, including novel examples, is synthesized and their transformations into the corresponding condensed heterocyclic compounds (2,3-dihydro-1H-pyrroles and 6,7-dihydro-5H-pyrrolo[2,1-b]thiazolium salts) are studied.
Keywords
Cyclopropylazoles , 2 , 2-Cyclopropylbenzothiazole , 2-a]imidazole , 2 , 1-b]thiazol-9-ium bromide , Antitumor activity , Cyclopropylimine rearrangement , green chemistry , 2-Cyclopropylbenzimidazole
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1874735
Link To Document