Author/Authors :
P. Cavalluzzi، نويسنده , , Maria Maddalena and Lentini، نويسنده , , Giovanni and Lovece، نويسنده , , Angelo and Bruno، نويسنده , , Claudio and Catalano، نويسنده , , Alessia and Carocci، نويسنده , , Alessia and Franchini، نويسنده , , Carlo، نويسنده ,
Abstract :
A simple, convergent synthesis of the N-carbonyloxy β-d-glucuronide of mexiletine (sodium salt) in moderate yield is described. The compound is now available as an authentic reference standard for analytical studies, enabling more detailed investigation on the metabolism of mexiletine.
Keywords :
Glycosidic linkage , Ring-opening reaction , Curtius rearrangement , Stereochemistry
