Author/Authors :
Kumar Reddy، نويسنده , , D. and Rajesh، نويسنده , , K. and Shekhar، نويسنده , , V. and Chanti Babu، نويسنده , , D. and Venkateswarlu، نويسنده , , Y.، نويسنده ,
Abstract :
A simple and highly efficient stereoselective total synthesis of cytotoxic agent sporiolide A has been achieved starting from d-mannitol; the strategy of synthesis utilizes stereoselective zinc-mediated allylation, aldol coupling and ring-closing metathesis as key steps.
Keywords :
Sporiolide A , aldol coupling , ring-closing metathesis , Zinc-mediated allylation