Title of article :
An organocatalytic route to the synthesis of lactone moiety of compactin and mevinolin
Author/Authors :
Kumar، نويسنده , , Pradeep and Pandey، نويسنده , , Menaka and Gupta، نويسنده , , Priti and Dhavale، نويسنده , , Dilip D.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
An efficient synthesis of lactone moiety of compactin has been achieved. The stereogenic centers were generated by means of iterative proline-catalyzed sequential α-aminoxylation and Horner–Wadsworth–Emmons (HWE) olefination of aldehydes.
Keywords :
lactone , proline , organocatalysis , Compactin , Aminoxylation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
