Author/Authors :
Iizuka، نويسنده , , Toshimasa and Takiguchi، نويسنده , , Satoshi and Kumakura، نويسنده , , Yuh-suke and Tsukioka، نويسنده , , Naoki and Higuchi، نويسنده , , Kazuhiro and Kawasaki، نويسنده , , Tomomi، نويسنده ,
Abstract :
We describe the first total synthesis of the reported and revised structures of okaramine M (1 and 7) through the Ugi three-component reaction of pyrroloindole imine 10 with p-methoxyphenyl isonitrile and N-Boc-l-tryptophan, followed by cyclization and epimerization.
Keywords :
asymmetric synthesis , Diketopiperazine , 3-b]indole , Oxidation
