Title of article
Synthesis of 2,3-dihydro-1,4-dithiinyl nucleosides via Pummerer-type glycosidation
Author/Authors
Paolella، نويسنده , , Concetta and D’Alonzo، نويسنده , , Daniele and Guaragna، نويسنده , , Annalisa and Cermola، نويسنده , , Flavio and Palumbo، نويسنده , , Giovanni، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
6060
To page
6063
Abstract
A straightforward procedure for the preparation of nucleoside analogue 1 and its regioisomer 2 containing a dihydro-1,4-dithiin as sugar moiety has been accomplished in four steps by our readily available heterocyclic system 5. Nucleobase insertion was carried out by direct addition of N4-acetylcytosine to sulfoxide derivatives via Pummerer-type glycosidation reaction.
Keywords
Heterocyclic nucleosides , Dithiins , Nucleoside analogues , Pummerer-type glycosidation
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1875512
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