Author/Authors :
Gracia، نويسنده , , Stéphanie and Jerpan، نويسنده , , Rudolf and Pellet-Rostaing، نويسنده , , Stéphane and Popowycz، نويسنده , , Florence and Lemaire، نويسنده , , Marc، نويسنده ,
Abstract :
The synthetic access to indolizidines, substituted in C-5 position, was reported with good diastereoselectivity. The strategy developed was based on a key step of Michael addition associated with a Clauson-Kaas condensation.
Keywords :
indolizidines , Michael addition , Multi-step synthesis , Alkaloids