Title of article :
Escherichia coli BioH: a highly enantioselective and organic solvent tolerant esterase for kinetic resolution of sec-alcohols
Author/Authors :
Wang، نويسنده , , Bo and Tang، نويسنده , , Xiaoling and Liu، نويسنده , , Ji and Yu، نويسنده , , Hongwei، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
Escherichia coli BioH, which is obligatory for biotin synthesis, was found to be an organic solvent tolerant esterase with high enantioselectivity for the kinetic resolution of sec-alcohols using free enzyme powder. With this esterase, a variety of racemic sec-alcohols were efficiently resolved with ee values of up to 99%.
Keywords :
Escherichia coli BioH , kinetic resolution , esterase , Enantioselectivity , organic solvent tolerance
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
