Title of article :
In situ, on-resin synthesis of 8-Br/NH2 adeninyl peptide nucleic acid (PNA) oligomers and complementation studies with DNA
Author/Authors :
Vysabhattar، نويسنده , , Raman and Ganesh، نويسنده , , Krishna N.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
A new, novel and efficient in situ synthesis of 8-aminoadeninyl PNA oligomers from corresponding 8-bromoadeninyl PNA oligomers is reported. The study of hybridisation properties of (8-Br/8-NH2) PNA oligomers with cDNA reveals substitution-site dependent stabilization of derived triplexes and duplexes.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
