Author/Authors :
Davies، نويسنده , , Deiniol and Fletcher، نويسنده , , Matthew D. and Franken، نويسنده , , Herjan and Hollinshead، نويسنده , , Jackie and Kنhm، نويسنده , , Kristina and Murphy، نويسنده , , Patrick J. and Nash، نويسنده , , Robert and Potter، نويسنده , , David M، نويسنده ,
Abstract :
The iodocyclisation of a range N-allyl and N-homoallylguanidines using I2/K2CO3 has been found to lead to a series of novel heterocycles which undergo selective rearrangements on variation of the reaction conditions, and predictable protecting group migration in the presence of trifluoroacetic acid in methanol.
Keywords :
iodocyclisation , Guanidine , Rearrangement , Ring contraction