Title of article :
Site-selective Suzuki–Miyaura reactions of 2,3-dibromo-1H-inden-1-one
Author/Authors :
Hussain، نويسنده , , Munawar and Hung، نويسنده , , Nguyen Thai and Khera، نويسنده , , Rasheed Ahmed and Villinger، نويسنده , , Alexander and Langer، نويسنده , , Peter، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
The first transition metal-catalyzed cross-coupling reactions of 2,3-dibromo-1H-inden-1-one are reported. The Suzuki–Miyaura reaction of 2,3-dibromo-1H-inden-1-one with 2 equiv of arylboronic acid gave 2,3-diaryl-1H-inden-1-ones. The reaction with 1 equiv of arylboronic acid gave 2-bromo-3-aryl-1H-inden-1-ones with very good site-selectivity. The one-pot reaction of 2,3-dibromo-1H-inden-1-one with two different arylboronic acids afforded 2,3-diaryl-1H-inden-1-ones containing two different terminal aryl groups.
Keywords :
Catalysis , PALLADIUM , Suzuki–Miyaura reaction , Site-selectivity , Indenones
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
