Author/Authors :
Chen، نويسنده , , Guofei and He، نويسنده , , Guangke and Xue، نويسنده , , Can and Fu، نويسنده , , Chunling and Ma، نويسنده , , Shengming، نويسنده ,
Abstract :
We have developed a facile and effective synthesis of 3-iodofurans from 3-monosubstituted 1,2-allenyl perfluoroalkyl ketones or 2-hydroxy-4-iodo-2,5-dihydrofurans from 3,3-disubstituted 1,2-allenyl perfluoroalkyl ketones. The perfluoroalkyl substituent and the amount of water in the solvent are important for the success of this electrophilic cyclization.