Author/Authors :
Savant، نويسنده , , Mahesh M. and Gowda، نويسنده , , Neetha S. and Pansuriya، نويسنده , , Akshay M. and Bhuva، نويسنده , , Chirag V. and Kapuriya، نويسنده , , Naval and Anandalwar، نويسنده , , Sridhar M. and Prasad، نويسنده , , Shashidhara J. and Shah، نويسنده , , Anamik and Naliapara، نويسنده , , Yogesh T. and Joshi، نويسنده ,
Abstract :
A highly efficient strategy to 2,3-substituted chromen-4H-ones has been developed. The methodology involves unexpected intramolecular heteroannulation of readily accessible substituted 2-hydroxy-ω-nitroacetophenone with carbon disulfide in the presence K2CO3 followed by methylation with methyl iodide. These chromenones were further reacted with various nucleophiles such as amines, thiols, and alkoxide resulting in the facile C–N, C–S, and C–O bond formation. The scope and generality have been discussed.
