Title of article :
An investigation of the bromination of 1,4-dihydropyridine rings
Author/Authors :
Rorlik، نويسنده , , Ori and Tashma، نويسنده , , Zeev and Barzilay، نويسنده , , Claudia M. and Srebnik، نويسنده , , Morris، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Conditions for bromination at the C3 and C5 positions of a 1,4-dihydropyridine (DHP) were investigated. The effect of base concentration, base type, reaction temperature, and solvent were examined. DHP derivatives with ester and amide moieties were synthesized and brominated. The bromine atoms can be replaced by other substituents, utilizing Suzuki cross coupling.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
