Title of article :
Pd-catalyzed asymmetric reactions using resorcinol- and hydroquinone-based P∗,P∗-bidentate diamidophosphites
Author/Authors :
Gavrilov، نويسنده , , Konstantin N. and Zheglov، نويسنده , , Sergey V. and Shiryaev، نويسنده , , Alexei A. and Groshkin، نويسنده , , Nikolay N. and Rastorguev، نويسنده , , Eugenie A. and Benetskiy، نويسنده , , Eduard B. and Davankov، نويسنده , , Vadim A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Readily available isomeric bisdiamidophosphites with P∗-stereocentres have been prepared using resorcinol and hydroquinone as simple and cheap starting materials. Palladium catalytic systems containing these P∗,P∗-bidentate ligands afforded 99% and 70% ees in asymmetric allylic substitution and desymmetrization processes, respectively. The influence of the precatalyst, substrate, nucleophile, and solvent on the enantioselectivity is discussed.
Keywords :
desymmetrization , PALLADIUM , Phosphorus ligands , Diamidophosphites , Asymmetric allylic substitution
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
