• Title of article

    Palladium-catalyzed amidation of 2-chloropyrimidines

  • Author/Authors

    Liusheng and Vimolratana، نويسنده , , Marc and Simard، نويسنده , , Jillian L. and Brown، نويسنده , , Sean P.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2011
  • Pages
    3
  • From page
    1020
  • To page
    1022
  • Abstract
    A mild and efficient Pd-catalyzed coupling of amides with 2-chloropyrimidines is described. The use of bidentate phosphines, such as Xantphos (7), as supporting ligands was found to be crucial for providing high yields of 2-(N-acylamino)pyrimidine coupling products 1.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2011
  • Journal title
    Tetrahedron Letters
  • Record number

    1877019