Author/Authors :
Ivan A. Shuklov، نويسنده , , Ivan A. and Jiao، نويسنده , , Haijun and Schulze، نويسنده , , Joachim and Tietz، نويسنده , , Wolfgang and Kühlein، نويسنده , , Klaus and Bِrner، نويسنده , , Armin، نويسنده ,
Abstract :
The epimerization of chiral lactides was studied in the presence of various homogeneous and heterogeneous bases. Some solvent/base systems were found to promote epimerization at room temperature efficiently. Side reactions such as polymerization were not observed or occurred only slowly. This new protocol offers the opportunity of the transformation of meso-lactide into rac-lactide. Therefore it can reduce the overall manufacturing costs of polylactides, a problem which currently hampers the broad application of those environmentally friendly polymers in a large scale.
Keywords :
Stereospecific polymers , lactide , Isomerization , Stereoisomers , Poly-lactic acid
