Title of article
α-Halogenation of carbonyl compounds: halotrimethylsilane–nitrate salt couple as an efficient halogenating reagent system
Author/Authors
Prakash، نويسنده , , G.K. Sxurya and Ismail، نويسنده , , Rehana and Garcia، نويسنده , , Jessica and Panja، نويسنده , , Chiradeep and Rasul، نويسنده , , Golam and Mathew، نويسنده , , Thomas and Olah، نويسنده , , George A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
5
From page
1217
To page
1221
Abstract
A mixture of chloro/bromotrimethylsilane and nitrate salt is found to be an effective reagent system for the α-chlorination/bromination of carbonyl compounds. The reaction occurs under mild conditions yielding the products in moderate to good yields.
Keywords
PTP inhibitors , chlorotrimethylsilane , Density functional theory , Nitryl chloride , Direct ?-halogenation
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877175
Link To Document