Title of article
Synthesis of 3-halo-2,5-disubstituted furans via CuX mediated cyclization–halogenation reactions
Author/Authors
Yazici، نويسنده , , Arife and Pyne، نويسنده , , Stephen G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
1398
To page
1400
Abstract
The Cu(I) halide (X = I, Br, Cl) mediated reactions of Cbz-protected cis-2-phenylethenyl-3-hydroxypyrrolidine gave novel 3-halo-2,5-trisubstituted furans in good yields, via a cyclization-halogenation, ring-opening reaction sequence. In contrast, the reactions with CuCN gave mainly the corresponding 3-cyanofuro[3,2-b]pyrrole formed from a cyclization–cyanation reaction.
Keywords
2 , 3 , 5-Trisubstituted furans , Cyclization–halogenation , Cyclization–cyanation , Cu(I) salts
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877314
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