Title of article
One-pot synthesis of 2-trifluoromethylchromones
Author/Authors
Castaٌeda، نويسنده , , Isabel C. Henao and Ulic، نويسنده , , Sonia E. and Védova، نويسنده , , Carlos O. Della and Metzler-Nolte، نويسنده , , Nils and Jios، نويسنده , , Jorge L.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
5
From page
1436
To page
1440
Abstract
We report a simple and suitable method for the preparation of useful 2-trifluoromethylchromones in one step, in high yields and avoiding the use of solvents. We were able to detect the intermediate of this reaction. Furthermore a mechanism for the formation of the 7-methoxy-3-trifluoroacetyl-2-trifluoromethylchromone through the unexpected double trifluoroacetylation of 4-methoxy-2-hydroxyacetophenone followed by dehydration is also proposed. All compounds are fully identified and characterized by spectroscopic techniques.
Keywords
one-pot synthesis , 2-trifluoromethylchromones , NMR characterization
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877341
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